NEW YORK, RAW – Wall Street stocks have ended sharply lower in a broad sell-off driven by rising US Treasury yields, deepening concerns over persistent inflation and contentious debt ceiling negotiations in Washington DC.

All three major US stock indexes slid nearly 2.0 per cent or more, with interest rate sensitive tech and tech-adjacent stocks weighing heaviest as investors lost their risk appetite.

It was the S&P 500 index’s biggest one-day percentage drop since May and the Nasdaq’s largest since March.

The S&P 500 and the Nasdaq Composite index were on track for their largest monthly declines since September 2020.

“The big picture is the sudden surge in the past week of yields, which has led to a ‘sell first, ask questions later’ mentality,” Ryan Detrick, senior market strategist at LPL Financial in Charlotte, North Carolina.

“(But) there are multiple factors weighing on sentiment today,” Detrick added.

“The back-and-forth in Washington with the debt ceiling and the spending bill and potential higher taxes have weighed on overall investor psyche and has led to a pretty good sized sell-off.”

The benchmark index was also setting a course for its weakest quarterly performance since the COVID-19 pandemic brought the global economy to its knees.

Weakness pervaded across most asset classes, including gold, suggesting widespread risk-off sentiment.

US Treasury yields continued rising, with 10-year yields reaching their highest level since June as inflation expectations heated up and fears grew that the US Federal Reserve could shorten its timeline for tightening its monetary policy.

Treasury Secretary Janet Yellen said she expected inflation to end 2021 near 4.0 per cent and warned lawmakers their failure to avert a government shutdown as the US moves closer to exhausting its borrowing capabilities could cause “serious harm” to the economy.

Senate Republicans appeared set to strike down Democrats’ efforts to extend the government’s borrowing authority and avoid a potential US credit default.

A Conference Board report showed consumer confidence weakened unexpectedly in September to the lowest level since February.

The Dow Jones Industrial Average fell 569.38 points, or 1.63 per cent, to 34,299.99; the S&P 500 lost 90.48 points, or 2.04 per cent, at 4,352.63; and the Nasdaq Composite dropped 423.29 points, or 2.83 per cent, to 14,546.68.

Half of the S&P 500’s components closed 10 per cent or more below their 52-week highs.

That included 63 stocks that had fallen 20 per cent or more.

Among the 11 major sectors of the S&P 500, all but energy ended red, with tech and communications services suffering the steepest percentage losses.

Communications services shed 2.8 per cent, the sector’s biggest one-day percentage decline since January.

The S&P growth index closed at its lowest since July and posted its biggest one-day percentage drop since February.

Microsoft Corp, Apple Inc, Inc and Alphabet Inc weighed heaviest on the S&P and Nasdaq, falling between 2.4 per cent and 3.6 per cent.

Ford Motor Co was one of the few bright spots, advancing 1.1 per cent on news that it would join South Korean battery partner SK Innovation to invest $US11.4 billion ($A15.7 billion) to build an electric F-150 assembly plant and three US battery plants.

Declining issues outnumbered gainers on the NYSE by a 4.35-to-1 ratio; on Nasdaq, a 4.52-to-1 ratio favoured decliners.

The S&P 500 posted 17 new 52-week highs and five new lows; the Nasdaq Composite recorded 54 new highs and 120 new lows.

Volume on US exchanges was 12.27 billion shares compared with the 10.37 billion average over the last 20 trading days.