The Dow Jones Industrials was on track for its biggest daily decline in two years and the S&P 500 fell more than 3 per cent on Monday, as investors fled riskier assets as fears about the global economic impact of the coronavirus intensified after a surge in cases outside China.

Several countries including Iran, Italy and South Korea reported a rise in virus cases over the weekend, fanning fears of a pandemic that also prompted a rush to safe-haven assets such as gold and US Treasuries.

A yield curve inversion between the 3-month and 10-year US Treasuries deepened in a classic recession sign. Adding to worries, Goldman Sachs slashed its US growth forecast and predicted a more severe impact from the epidemic, CNBC reported.

The blue-chip Dow erased its gains for the year, while the benchmark S&P 500 was almost 2 per cent below its intraday record high hit on Thursday. The Nasdaq was almost 6 per cent off its record peak.

All of the 11 major S&P sectors were in the red, led by the energy sector’s 4 per cent decline and followed by a 3.4 per cent drop in technology stocks.

Apple Inc slid 3.5 per cent as data showed sales of smartphones in China tumbled by more than a third in January.

Wall Street’s main indexes had notched record highs last week, partly on optimism that the global economy, supported by central banks, would be able to snap back after short-term weakness related to the virus.

The CBOE Volatility Index, a gauge of investor anxiety, jumped to its highest level since January 2019.

“There was this underlying concern that was out there, and obviously over the weekend, it just escalated,” said Stacey Gilbert, portfolio manager for derivatives at Glenmede Investment Management in Philadelphia.

The Dow Jones Industrial Average fell 929.04 points, or 3.2 per cent, to 28,063.37, the S&P 500 lost 101.65 points, or 3.05 per cent, to 3,236.1 and the Nasdaq Composite dropped 329.49 points, or 3.44 per cent, to 9,247.10.

China-exposed chipmakers slipped, with the Philadelphia SE Semiconductor index dropping 4 per cent, while concerns about growing travel curbs dragged the NYSE Arca Airline Index down 6.4 per cent.

The S&P 500 fell below its 50-day moving average and the Dow slipped below its 100-day moving average, all closely watched indicators of momentum.

Health insurers such as UnitedHealth Group Inc and Cigna Corp dropped around 7 per cent as Bernie Sanders, who backs the elimination of private health insurance, strengthened his position for the Democratic presidential nomination with a victory in the Nevada caucuses.

“I think markets are repricing the probability of a Sanders (nomination),” Darrell Cronk, chief investment officer of Wells Fargo Wealth & Investment Management said during a conference call with investors.

In a rare bright spot, Gilead Sciences Inc, whose antiviral remdesivir has shown promise in monkeys infected by a related coronavirus, rose 3.3 per cent.

Declining issues outnumbered advancing ones on the NYSE by a 6.44-to-1 ratio; on Nasdaq, a 6.82-to-1 ratio favoured decliners.

The S&P 500 posted 7 new 52-week highs and 22 new lows; the Nasdaq Composite recorded 19 new highs and 147 new lows.