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The ASX has closed down after CSL’s decision not to progress its coronavirus vaccine and because of the big banks, but investors still had a sixth week of gains.

The S&P/ASX200 benchmark index closed lower by 40.5 points, or 0.61 per cent, to 6642.6 on Friday.

The All Ordinaries closed down 30.7 points, or 0.44 per cent, to 6886.4.

CSL and the University of Queensland’s decision not to undertake a second trial of their vaccine candidate was the main story of the day.

Some trial participants returned false positive results for HIV.

CSL fell 3.24 per cent to $291.53.

Yet investors can still be satisfied with gains of 0.13 per cent for the week on the ASX200.

Before trade, Wall Street markets mostly fell following the largest number of unemployment claims in three months, high numbers of COVID-19 infections, and US politicians unable to strike an economic stimulus deal.

The Aussie dollar was buying 75.57 US cents at 1627 AEDT, higher from 74.77 US cents at Thursday’s close.